Today, the cast and creator of The 100 gathered in San Diego Comic-Con to discuss the fallout from last season and tease a little bit of what’s ahead. And we were promised a more science fiction plotline for season three as well as the characters dealing with grief, guilt, and disability.

Spoilers through season two of The 100 ahead.

“Season three is as different from season two as season two was from season one,” said The 100 creator Jason Rothenberg to the audience in the San Diego Convention Center’s Ballroom 20. After the Arkers landed on Earth at the end of season one, the show lost its space setting, and Rothenberg missed what he called that “hardcore science fiction” element. The second season finale introduced Jaha (and us) to an artificial intelligence—with a beautiful female avatar—who apparently had a hand in the show’s apocalypse, and that will lead us into a new, more science fictional storyline.

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The third season takes place a few months after Clarke left her fellow Sky People in the wake of the destruction of Mount Weather. “She’s finding herself,” actress Eliza Taylor said. “What she did at the end of the season was so huge and traumatic. So she’s running away, which is very un-Clarke-like.”

Bellamy, meanwhile, will have to step up in Clarke’s absence. While Clarke is dealing with her guilt over the deaths at Mount Weather, Bellamy doesn’t have time for emotional wallowing. “He has to look at the 44 on his own,” Bob Morley said. “He has to get on with it.”

Raven, meanwhile, has to deal with the physical consequences of the Mount Weather war. Actress Lindsey Morgan says that one of the great things about portraying Raven has been finding the character’s strength to live and operate even through physical disability. But Raven was injured again at the end of season two and that will cause major issues for her in season three. “Raven is, as much as she doesn’t want to admit it, delicate,” Morgan notes. “She’s worse off after the bomb, living her life without finn, feeling her grief. You’re going to see a new raven. She’s trying to put herself back together piece by piece.”

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After severing ties with the Grounders, Octavia finds herself feeling resentful towards the Arkers. But it’s Lincoln who is the real outsider, a Grounder living among the Arkers. After all, most Arkers see Grounders only as the people who have killed their friends and family. They’ll see Lincoln as a monster, something he’ll have to live with. Still, actor Ricky Whittle says he’ll be the same old Lincoln. “His moral compass has never changed, has never wavered. I don’t think anything is going to change. His life is a war. His body is a roadmap of pain.”

And is there hope of a reconciliation between Clarke and the Grounder commander Lexa? “I suppose,” said Rothenberg, revealing that actress Alycia Debnam-Carey will be returning in season three. But when she and Clarke meet again, the fireworks that fly won’t be romantic. “Clarke is pissed.”