Our cells lock up Shigella bacteria in cages to stop it from killing us

Illustration for article titled Our cells lock up Shigella bacteria in cages to stop it from killing us

Shigella is an incredibly nasty bacteria related to E coli and Salmonella, and it's only found in apes — including us humans. When we get infected, it can cause lethal dysentery, so we've evolved a cunning way of fighting off the bug, a technique which has only just been observed. The human cells attack the invading Shigella using septin — a protein that's part of the cell's skeleton. The septin envelopes the bacteria; prevents it from spreading by limiting its access to actin, which it requires to move around; and marks it for destruction by autophagy, the cell's garbage disposal system.

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This research is being presented at The American Society for Cell Biology 51st Annual Meeting this December, and it marks a novel discovery in the way our bodies fight off invaders. Throwing a cage around something and having it killed off is a pretty metal way to defend against disease!

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DISCUSSION

/rant

Could this be so beautiful that only an intelligent creator made it...?

Or...

Could lethal dysentery kill those that don't have this feature and those that do live?

***

I'm always confused about how a doctor can be religious (not spiritual, but religious). Take Francis Collins, geneticist, director of the National Institute of Health, a believer in evolutionary creation ( [en.wikipedia.org] ). If it dies disproportionally, then it doesn't reproduce as much. Those that live, can reproduce. Why does this need another explanation? Why is this prima facie evidence of a something else creating it?

How can someone believe in the scientific method, be open to criticism of all the facts based on knowledge and still assert that believe without evidence make sense?!?!!!!

/endrant