The short answer? An absolutely comical amount, perhaps lit by a jet engine. It would also help if you owned a residence in Toontown or were physically a Tex Avery illustration. In a 1988 DEA brief, Judge Francis Young did the math and broke down just how much sticky-icky it would take to off you entirely:

It is estimated that marijuana's [median lethal dose] is around 1:20,000 or 1:40,000. In layman terms this means that in order to induce death a marijuana smoker would have to consume 20,000 to 40,000 times as much marijuana as is contained in one marijuana cigarette. [National Institute on Drug Abuse]-supplied marijuana cigarettes weigh approximately .9 grams. A smoker would theoretically have to consume nearly 1,500 pounds of marijuana within about fifteen minutes to induce a lethal response.


Young goes on to surmise, "In practical terms, marijuana cannot induce a lethal response as a result of drug-related toxicity." But what if you actually wanted to, in completely impractical terms? I imagine that you would have to build a hotbox the size of a ziggurat and ignite your stash via orbital laser.

Via Dangerous Minds. Top song ‚ÄĒ Scientist's "Your Teeth In My Neck" from Scientist Rids the World of the Evil Curse of the Vampires ‚ÄĒ because I wanted to listen to it.