Schizophrenia is a complex disease with elusive origins, but the mystery became much clearer today, when a landmark new study based on genetic analysis of nearly 65,000 individuals pinpointed a specific gene and biological process behind it.
For a long time, people with schizophrenia have reported feeling as though their thoughts and actions were controlled by an outside influence, and people didn’t understand why. One experiment, involving crickets, may have shed some light on the neurology behind that feeling.
Thorazine, or chlorpromazine, was the first antipsychotic. It freed many people with severe schizophrenia from mental asylums, but that's not why it was developed. It was first tested because it's an antihistamine. Yes, like the allergy medications.
A Southern California murder trial would be just another tragic tale of neighbor shoots neighbor, except the accused believes that he is a werewolf ... and he believed his victim was a vampire, according to the testimony of a forensic psychologist.
Last month, a study published in the American Journal of Psychiatry made international headlines by claiming that schizophrenia is not a single disease, but rather a group of eight distinct genetic disorders. Now, ten leading geneticists say this extraordinary claim isn't justified by the data.
Do mental illnesses have certain eras? When we look at history, it seems like they do. There was the famous dancing sickness that struck medieval Europe. And then there was a strange delusion, first experienced by a king, in which the sufferer thought they were made of glass.
New research published in the American Journal of Psychiatry suggests that schizophrenia is not a single disease, but rather a group of eight genetically distinct disorders, each of them with its own set of symptoms. The finding could result in improved diagnosis and treatment, while also shedding light on how genes…
A 1955 experiment attempted to prove that spiders could be used to diagnose schizophrenia. Although upsetting for everyone involved, the experiment was even less pleasant for the spiders than it was for the humans.
Elyn Saks first started noticing that something was wrong when she was 16. One day, and without reason, she suddenly left her classroom and started walking home. It turned into an agonizing journey in which she believed all the houses in her neighborhood were transmitting hostile and insulting messages directly into…
For the first time ever, researchers will conduct a detailed study of the DNA of a mass killer. By taking a closer look at Adam Lanza's genomic data, scientists are hoping to discover the potential biological underpinnings for extreme violence. But given the diverse nature of mental illness and the complex interplay…
As humans, it's only natural for us to search for explanations in the face of senseless violence. So it's no surprise that people have floated many weird and offensive theories to explain the tragic shootings late last week at a movie theatre in Colorado, that left 12 people dead and dozens more injured.
Studies of drugs that treat schizophrenia, what are also known as antipsychotics, are having fewer effects over time — and it's not because these drugs are becoming any less effective. Rather it's because patients are responding better to placebos – and it's not immediately obvious why this is happening.
File this under "things that should be self-evident", but new research has come out showing that the reason people occasionally gouge their own eyes out isn't because they want to have sex with their mother, or due to Christian religious guilt — it's because of psychotic illness.
Schizophrenia is among the most damaging and least understood of all mental disorders. Now a seemingly minor symptom — the fact that many schizophrenia patients complain of sleeping problems — could actually provide a crucial key to unraveling the disease.
Scientists have long searched unsuccessfully for the genetic factors that cause schizophrenia. Now we know why: the disorder is actually caused by what happens in cells around the genes. That knowledge could give us our best treatment yet for schizophrenia.
RM had his first out-of-body experience at the age of 16. Now, at the age of 55, he has had more than he can count. They usually happen just before he falls asleep; for ten minutes, he feels like he is floating above his body, looking down on himself. If the same thing happens when he's awake, it's a far less tranquil…
The single-celled parasite Toxoplasma gondii lives infects rats, but it needs to be inside a cat's digestive system in order to reproduce. The parasite actually alters the brain of its rat host so that it won't be afraid of cats.
Researchers testing mental illness figured out how to induce schizophrenic symptoms in a computer, causing it to place itself at the center of crazy delusions, such as claiming responsibility for a terrorist bombing.
What you're looking at are neurons grown from a schizophrenic person. An incredible study, published today in Nature, reveals how scientists grew schizophrenic brain cells to understand the inner workings of this still-mysterious neurological disorder.
You can't judge books by their covers, but you can judge scientific papers by their titles. Consider: "The planetary positions and relationships at the dates of birth of a cohort of Nigerian schizophrenics." Yeah, this is going to get weird.