Krokodil: Russia's Designer Drug That Will Eat Your FleshKeith Veronese11/15/11 3:00pmFiled to: Holy crap wtfMedicineScienceDrugsDesigner DrugsTopkrokodil2154EditPromoteShare to KinjaToggle Conversation toolsGo to permalinkIt sounds like a direct-to-Netflix horror movie plot — a cheap, addictive drug available in a foreign land, that turns the user's skin a scaly green color. Soon it rots the flesh, causing the user's skin to emulate that of a crocodile, leaving bone and muscle tissue exposed to the world. But the Russian drug known as krokodil is real.AdvertisementWarning: Disburbing images of the effects of Krokodil below. This article may be shocking or upsetting for some people. Please proceed with caution. Top image via fritscdejong on Flickr.AdvertisementYouTube videos emanating from Russia displaying the aftereffects of Krokodil use have been available for months. The clips often spotlight the gore factor, displaying the gangrene, exposed bones, and scale-like skin that lent the drug its name. What makes people use a drug that will destroy their body, to the point where their bones are exposed and require amputation? Why is usage (so far) contained to Russia?What is in Krokodil? Just as crack is the broke addict's cocaine, krokodil is a substitute for a much more expensive drug, heroin. The chemical behind krokodil, desomorphine, was available as a morphine substitute shortly after laboratory synthesis in 1932. Desomorphine is 8-10 times more potent than morphine. The medicinal use of desomorphine was concentrated to Europe, particularly Switzerland. The synthetic opiate has a structure nearly identical to heroin.Codeine, a readily available narcotic, can be turned into desomorphine in a relatively easy series of chemical reactions, and then injected intravenously by the user. Whereas heroin may cost $150 US and up per use, krokodil can be obtained for $6-$8 US per injection.How is Krokodil made? The problem is not necessarily desomorphine addiction, it's the fact that krokodil users are unable to make a pure enough final product prior to use. When performed in a lab, the transformation of codeine into desomorphine is a rather easy, three step synthesis. When cooked in a kitchen lab, however, krokodil users often lack for materials, and thus use gasoline as a solvent along with red phosphorous, iodine, and hydrochloric acid as reactants to synthesize desomorphine from codeine tablets.AdvertisementSponsoredThe final product is often an impure, orange-colored liquid, with this impurity causing skin irritation, a scale-like look, and eventual destruction of the skin. This is likely due to the presence of hydrochloric acid still in the final liquid solution prior to injection, with red phosphorous, obtained by solvating and removing the "striker" portion of matchboxes, playing a role in furthering sickening the user. Once the skin around the injection site is damaged, the area becomes a target for gangrene. This leads to skin decay around the injection site, and, in time, the skin sloughs off, often exposing the bone below. Addiction is a full time job The high associated with krokodil is akin to that of heroin, but last a much shorter period. While the affects of heroin use can last four to eight hours, krokodil users are lucky to get an hour and a half of bliss, with the symptoms of withdrawal setting in soon after. Krokodil takes roughly 30 minutes to an hour to prepare with over-the-counter ingredients in a kitchen.The short time table causes addicts to be trapped in a full time, twenty-four hour a day cycle of cooking and injecting in order to avoid withdrawal. Once someone becomes addicted, it is common for the individual to die within two-three years of heavy use from exposure and associated health issues, with many dying within a year. Why is use prevalent in Russia? The major reason krokodil use is confined to Russia is due to the availability of codeine for purchase without a prescription — anyone can walk into any pharmacy and buy tablets containing the starting point of krokodil synthesis. Access could quickly be cut off by making codeine containing analgesics a prescription-only pharmaceutical in Russia. This has been met with backlash from citizens, as most believe that krokodil users will find another avenue for codeine, while preventing "proper" users from obtaining the analgesic tablets.A lack of government infrastructure also plagues krokodil users. Russia lacks a significant state-sponsored rehabilitation system, nor have they made any significant moves to ban the over the counter sale of codeine tablets. Speaking on this subject, Viktor Ivanov, head of Russia's Drug Control Agency, said:AdvertisementAdvertisementA year ago we said that we need to introduce prescriptions [...] These tablets don't cost much but the profit margins are high. Some pharmacies make up to 25 per cent of their profits from the sale of these tablets. It's not in the interests of pharmaceutical companies or pharmacies themselves to stop this, so the government needs to use its power to regulate their sale.Withdrawal symptoms can last up to month, making it a rather difficult habit to kick. It takes a phenomenal amount of will power to put up with the physical pain of withdrawal for a month than go to the kitchen and make another dose. Rehabilitation systems are present, with the vast majority religious-based due to the lack of government involvement.Apart from wanting to name this article In Soviet Russia, Drugs Eat You, there is not a lot to laugh about in regards to krokodil. It is a debilitating, body-destroying drug that's consumed predominantly by the poor. Reports of usage in Germany have also surfaced as of October 2011, where codeine drugs require a prescription. Codeine products have been considered "prescription only" narcotic for decades in U.S., the UK and Sweden. But pills containing codeine can still be purchased without a prescription in a Canada, Australia, Israel, France, and Japan. We may soon see the devastating effects of krokodil in these regions too.AdvertisementImages of Krokodil use courtesy of stopnarkotik.com.ua and youtube user kay8x. Sources linked within article.