Will the Neo-Depression Create a Drug Epidemic? Many economic crisis periods in the U.S. have spawned drug epidemics. During the late-nineteenth century "long depression" or "crisis," the use of opium reached epidemic proportions , and a few decades later the innovation of intravenous injection made heroin the drug of choice among 1930s Depression-era junkies. Heroin made a comeback during the 1973 Oil Crisis , while cocaine and crack use spiked directly after the early 1980s Recession . Meth was the drug of choice during the early 1990s recession , and we're sure to get another dose as the Neo-Depression of the early twenty-first century marches on. We've got some ideas about what drug it might be — and you can offer your opinion in our poll below.