You take a shambling horror from a Lovecraft story, pop a couple of shoulder cannons on it and a replace a few tentacles with laser beams, and you've got yourself a whole new kind of horror: CthulhuTech.
According to the CthulhuTech Web site:
CthulhuTech is an innovative storytelling game that started out as a combination of two popular genres. The first was that of cosmic horror, made popular by H. P. Lovecraft and culminating in the modern day with elements of Mike Mignola's Hellboy and John Carpenter's In the Mouth of Madness. The second was that of giant mecha Japanese animation, made popular by such series as Robotech, Neon Genesis Evangelion, and Rahxephon.
Personally, we can't think of many things scarier than a 500 foot tall monster sporting tech weapons. If it had another fearsome baddie to square off against, you could sell popcorn and front row seats for miles.
In fact, Paramount if you're still listening, just give the Cloverfield monster some sort of a blaster or missile pod in the sequel. Then we promise we won't complain. Check out Wildfire's CthuhuTech game on their site, where you can order everything you need to open dimensional portals and summon demonic forces. We didn't see any Shoggoths with armaments, but when you combine these two genres, you just know it's coming.